Orignal Paper : The effect of hot and cold temperature on the expression of nitric oxide related signal factors in the rat skeletal muscle during acute exercise |
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Abstract |
The purpose of this study was to investigate the effect of hot and cold temperature on the expression of nitric oxide related signal factor in the rat skeletal muscle during acute exercise. Male Sprague-Dawley rats (n=60) were randomly assigned to one of three temperature groups (normal=20℃, hot=34℃, cold=4℃). The Rats ran the treadmill running for the intensity of 90min at 26M/min with slope degree 10°. Solues and extensor digitorum longus muscle were exercised during the given exercise(30, 60, 90min). The western blotting and ELISA analysis were performed for the expression of nitirc oxide(NO), eNOS, GC, and PKG protein. The NO expression was not significantly decreased in cold and hot temperature. However, eNOS, GC, and PKG protein were significantly decreased in cold and hot temperature. In this study, eNOS, GC, and PKG protein expressions were affected by cold and hot temperature. Cold and hot temperature can affect the vasodilation of vascular muscle cells through the changes in NO related vasodilation signal factors. |
Key Words:
NO, eNOS, GC, PKG, Hot and cold temperature |
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