| Articles : Effects of a Combined Treatment of Isoflavone Diet and Aerobic Exercise on Blood Lipids Profile, Nitric Oxide, and Paraoxonase in Ovariectomized Rats |
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| Abstract |
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The purpose of this study was to examine the effects of a combined treatment of isoflavone diet and aerobic exercise on blood lipids profile, nitric oxide, and paraoxonase in ovariectomized S.D rats (30 weeks) during 12 weeks. Ovariectomized S.D rats were devided into four groups (BD, BEX, ID, 1EX). The exercise and nonexercise group were fed a diet containing isoflavone or basal diet. The exercise group performed exercise on treadmill to grade 0%, 16-17 m/min for 30 minutes, four days per week during 12 weeks. Results of this study were following. 1. Isoflavone diet significantly decreased serum total-cholesterol, triglyceride, LDL-C level (p＜0.05) and increased paraoxonase (p＜0.05). 2. Aerobic exercise significantly decreased total-cholesterol, triglyceride level (p＜0.05). 3. Combined treatment of isoflavone diet and aerobic exercise significantly decreased serum total-cholesterol. triglyceride level (p＜0.05, 0.01). and increased nitric oxide (p＜0.05). Consequently, it is suggested that isoflavone diet and aerobic exercise decrease serum total cholesterol, triglyceride, and low density liporotein cholesterol and increase serum nitric oxide and paraoxonase. therefore, it would have positive effects on cardiovascular disease ano atherosclerosis. |
| Key Words:
Ovariectomized rat, Isoflavone, Exercise |
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