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Journal of Exercise Nutrition & Biochemistry 2004;8(2):165-170.
Articles : Effect of Long Distance Running on Gastrointestinal Hormone
The purpose of this study was to determine the effect of long distance running on the level of gastrointestinal hormones such as gastrin which stimulates the secretion of gastric acid, insulin and glucagon which affect glucose metabolism as well as the level of glucose. Method: Twenty four long distance runners (male 16, female 8) participated in this study. Studies were performed after an overnight fasting. The levels of gastrin, insulin, glucagon, and glucose in blood were measured at 30min before and after exercise, and then they were measured again at 24 hr after 10 km race. Result: Plasma gastrin level was increased immediately after exercise (p<0.05), while no significant changes were observed before and after 24 hours of exercise. Plasma insulin level was decreased immediately after exercise (p<0.05). Plasma glucagon level was elevated immediately after exercise (p<0.05). However, there was no significant difference in the level of plasma glucose level during the study period. Conclusion: These results indicate that the elevated level of gastrin in long distance runner may be involved in acid-related gastrointestinal disease. The changes of insulin and glucagon levels may represent the constant blood glucose level and further imply the fine regulatory mechanism of glucose homeostasis in blood during short time exercise in long distance runners.
Key Words: Gastrin, Insulin, Glucagon, Glucose, Long distance runner


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