| Articles : The effect of exercise and taurine supplementation on body weight, blood glucose, insulin and cholesterol levels in streptozotocin induced diabetic rats |
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| Abstract |
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Exercise and taurine has been known to be benficial to the diabetic patients. But it combinatory effect has not been studied. This study aims to understand whether taurine intake has a repressive effect on blood levels of glucose, insulin and lipids of the streptozotocin-induced hyperglycemic diabetic rat, and also whether combinational treatment of taurine intake and low-intensity exercise has a synergistic repressive action. Taurine was freely supplied as 1 % solution. The blood glucose level was not suppressed in the taurine-intake diabetic rat, but the blood levels of insulin and lipid such as total colesterol, HDL-cholesterol, LDL-cholesterol and triglyceride was reverted. Exercise (25 mill/day, 5 time/week,15 m/min) alone has a repressive effect on the hyperglycemic index. The combinatory effect of taurine and exercise before and after streptozotocin injection was examined. When taurine was supplemented with exercise before streptozotocin injection, the blood glucose level was surprisingly unchanged. but the blood levels of insulin and lipids were mildly recovered. When taurine was supplemented with exercise after streptozotocin injection, the blood glucose level was also unchanged, but the blood levels of insulin and lipids were mostly recovered. These results suggest that taurine itself has no beneficial effect on the blood glucose level and no combinatory effect with exercise, although it has a positive effect on the blood insulin levels and also serum lipids. |
| Key Words:
streptozotocin induced diabetes, exercise, taurine, blood glucose, insulin, serum lipids |
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