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Journal of Exercise Nutrition & Biochemistry 2003;7(1):23-30.
Articles : Effect of Endurance Exercise on SOD, GSH-Px activity and Oxidized LDL in Diabetic rats
Abstract
The purpose of this study was investigated the effect of 30minutes endurance exercise (16-17m/min) on vitamin E, selenium concentration. SOD, GSH-Px activity and oxidized LDL in streptozotocin induced diabetic rats. It were divided diabetes (n=12) and control group (n=12) for antioxidant capacity. The results were obtained which were analyzed vitamin E, selenium in liver, SOD, GSH-Px activity in mitochondria of liver and oxidized LDL in rest and post-exercise of each group, exercise time. The results of this study was summarized as the follows. Blood glucose and vitamin E, selenium concentration in liver showed significant differences. SOD, GSH-Px activity in mitochondria of liver showed any significant differences between two groups. Each exercise time, diabetes group in SOD decreased in post-exercise but control group increased GSH-Px of all group decreased any significant in post-exercise. When LDL was oxidized by each times showed any significant differences between two groups except 60minutes. Also, it was showed that diabetes group is decreased in post-exercise test. These results indicate that diabetes group was showed specific decrease antioxidant defense system by free radical of hyperglycemia. Especially 30minutes endurance exercise was decreased blood glucose concentration, Furthermore it was examined the effect of oxidized LDL which arteriosclerosis index decreased any significant. Future study is required to multiples research the effect of antioxidant and exercise teratment in diabetic rats.
Key Words: oxidized LDL, streptozotocin, arteriosclerosis


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