Review : Exercise and L - Carnitine

Journal of Exercise Nutrition & Biochemistry 2001;5(1):1-12.

Abstract

C
arnitine is synthesized in mammals with lysine and methionine providing the carbon backbone of the molecule. Dietary carnitine also contribute to the cannitne-pool in man, but endogenous biosynthetic capacity is adequate to meet body requirments under normal conditions. As muscle does not contain the enzyme for the terminal steps in carnitine biosynthesis, muscle carnitine is derived from diet or synthesis by the liver or kidney. Carnitine is transported to the muscle in plasma, and enters the muscle via an active transport system. Recently it has been shown that L-carnitine in transport of Acyl-CoA through the inner mitochondrial membrane, which activating of β-oxidation in long-chain fatty acids, induce of glycogen sparing effect, known as enhanced exercise and regularly training. Actually, L-carnitine is not consistent of applied exercise situation. Therefore, we think that exercise performance and L-carnitne administration is need to study ahead of a lateral face in multiple.