Effects of Training Exercise and Caffeine Ingestion on Energy Substrates and Glycogen Content in Rats

Journal of Exercise Nutrition & Biochemistry 1998;2(1):77-87.

Abstract

C
affeine has been used as an ergogenic aid to most of endurance athletes. As this point of view, we hypothesized that caffeine and training exercise could affect the glycogen contents in skeletal muscle and serum energy substrates in rats. Forty-eight male sprague-dawley rats had taken treadmill exercise at 28m/min/30min for 5days of week during 4wks. At the experimental day, all rats, except sedentary group(sed, n=12), were ingested 50㎎/㎏ of caffeine using round-ended needle directly into the mouth. They were killed at pre(pre-exercise group), 1hr(1hour exercise group), and 2hr(2hours exercise group) exercise and were followed by sed rats. Serum glucose, TG, FFA, and glycerol concentrations were analyzed and liver, soleus, gastrocnemius white muscle glycogen contents were determined. Serum FFA and glycerol were increased but glucose was decreased following exercise. Liver and muscle glycogen were not changed. In conclusion, even though serum FFA and glycerol increased, glycogen-sparing effect was not occurred. And, we thought that further research and discuss will be needed.